Salmon calcitonin induced head twitch in the rat.
نویسندگان
چکیده
The intracerebroventricular administration of salmon calcitonin (sCT) to rats induced a dose-dependent increase in the number of head twitches and potentiated such a response elicited by L-5-hydroxytryptophan (L-5-HTP). Subcutaneously administered sCT was ineffective "per se" but could again potentiate the head twitch response elicited by L-5-HTP. Since these data suggest a stimulation of the brain serotonergic pathways, the obtained results support the hypothesis that some central actions of sCT may involve activation of serotonergic systems in the rat brain.
منابع مشابه
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ورودعنوان ژورنال:
- Japanese journal of pharmacology
دوره 47 1 شماره
صفحات -
تاریخ انتشار 1988